Empty Sella

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Empty Sella

Empty Sella

Question: What is empty sella, and is it common?

Answer: Empty sella is defined by CSF filling the sella region on imaging with a flattened appearance of the pituitary gland. MRI studies report a wide frequency range of approximately 8–35%.

Practical approach when an empty sella report is received:

  1. If symptoms are present (headache, visual complaints, hormonal signs): physician evaluation
  2. Endocrine tests if needed
  3. Decision on follow-up or treatment based on clinical findings plus test results

What does “Empty Sella is present” mean?

Empty sella refers to a condition in which the sella turcica—the bony cavity that contains the pituitary gland—appears partially or completely filled with cerebrospinal fluid (CSF). The pituitary gland itself usually appears flattened or reduced in size.

Is Empty Sella Syndrome dangerous?

In most cases it does not pose an immediate danger; however, it is not considered trivial. When detected, a comprehensive evaluation is recommended, including:
Hormonal profile
• Fundoscopic (eye fundus) examination
• Advanced MRI assessment
This approach helps with early detection of associated conditions such as pseudotumor cerebri or CSF leak.

What is the treatment for empty sella?

Empty sella alone usually requires supportive follow-up.
• If hormone deficiencies are present, hormone replacement therapy is given.
• If visual risk, CSF rhinorrhea (CSF leakage from the nose), or meningitis risk develops, surgical options may be considered.